Category: Matter

Things that matter, such as professional work or published writing.

Contact Tracing

Post author By Michael A. Castello
Post date December 22, 2020

While only as good as the number of users opted in, contact tracing apps can help identify people at risk of COVID-19 exposure. Continue readingContact Tracing

Tags covid.19, reference.information

Matter Science

Objections to Prevention

Post author By Michael A. Castello
Post date July 20, 2020

"Rationing means a fair share for all of us." Fair? That sounds like socialism!

A rundown of objections to COVID-19 prevention strategies, and why those objections are wrong.Continue readingObjections to Prevention

Tags clinical.medicine, covid.19, health

Matter Science

Rule In, Rule Out

Post author By Michael A. Castello
Post date July 17, 2020

Setting the cutoff at A represents 100% sensitivity. All positives (pink curve) are true positives, but some negatives are false negatives (purple shading). Moving the cutoff to C represents 100% specificity. All negatives (blue curve) are true negatives, but some positives are false positives. Setting a cutoff in the middle at B is a compromise between the two.

Looking at false positives, false negatives, and what that means for COVID-19 testing.Continue readingRule In, Rule Out

Tags clinical.medicine, covid.19, research

Matter Science

A Headache of a Headache

Post author By Michael A. Castello
Post date April 29, 2020

Clinical case presentation given in partial fulfillment of the UCSD Child Neurology residency program. Among other things, working through this particular case emphasized the broad differential diagnosis of aseptic meningitis. Available on Google Slides or…Continue readingA Headache of a Headache