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Lipid Regulation as a Critical Factor in the Development of Alzheimer’s Disease
PhD Thesis Defense presented by Michael A. Castello on Friday, September 5, 2014.
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APP Regulates Brain Lipid Homeostasis
Presentation at Neuroscience 2013; November 10, 2013. Available on Prezi or for download.
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Unveiling Pathogenic Mechanisms in Niemann-Pick Type C Disease
Presentation for Parseghian Foundation Conference 2013. Available on Prezi or for download.
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Testing an Adaptive Response Hypothesis of Alzheimer’s Disease
Loma Linda University Monday Seminar presentation, February 11, 2013. Also available on Prezi or for download.
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PhD Candidate!
Yesterday I presented and defended my PhD thesis. Spoiler: I passed! I’m now a PhD candidate, meaning that the only thing standing between me and my first doctorate…is more than a year of dedicated research. It’s kind of a big deal, as they say, so I’m going to allow a bit of self-satisfaction. A big…
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Cholesterol Dysregulation and Neurodegenerative Disease
Thesis proposal by Michael A. Castello, presented on October 26, 2012.
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Snapshot of a Researcher: Dr. Soriano
At least one person has told me her view of scientists was that they were all crazy white-haired men with accents. It got me thinking—I think that picture is close to a majority opinion. Indeed, if you do a Google image search for “scientist,” one of the first results is pretty much exactly that. As others…
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Science at 100x
Because you were so consumed with longing to know what I do in lab all day, here’s a picture of some immunofluorescence staining I’ve been working on. Blue is cholesterol (labeled with filipin), which has accumulated in these cells as a result of treatment with a special drug. Red and green are two proteins I’m…
Matter, Energy, and Life of Michaela A. Castello.